8-OH-脫氧鳥嘌呤

生物活性靶點(diǎn)體外研究 用途與合成方法 MSDS 8-OH-脫氧鳥嘌呤價(jià)格(試劑級(jí)) 上下游產(chǎn)品信息

中文名稱	8-OH-脫氧鳥嘌呤
中文同義詞	8-OH-脫氧鳥嘌呤;8-羥基-2'-脫氧鳥嘌呤;2'-脫氧-7,8-二氫-8-氧代鳥苷;8-羥基-2-脫氧鳥苷;8-羥基脫氧鳥苷;2'-脫氧-8-氧代鳥嘌呤;8-氧-2'-脫氧鳥苷;核酸氧化8-羥基脫氧鳥苷
英文名稱	8-OXO-2'-DEOXYGUANOSINE
英文同義詞	8-HYDROXY-2'-DEOXYGUANOSINE;2'-Deoxy-8-oxoguanosine;7,8-Dihydro-8-oxo-2'-deoxyguanosine;8-Oxo-7,8-dihydro-2'-deoxyguanosine;8-Oxo-7,8-dihydrodeoxyguanosine;2'-Deoxy-8-oxo-D-guanosine;8-Oxo-7,8-dihydro-2μ-deoxyguanosine,  8-Oxo-dG;2'-Deoxy-8-hydroxyguanosine
CAS號(hào)	88847-89-6
分子式	C10H13N5O5
分子量	283.24
EINECS號(hào)
相關(guān)類別	合成;Bases & Related Reagents;Labeling and Diagnostics Reagents;Nucleotides;Heterocycles
Mol文件	88847-89-6.mol
結(jié)構(gòu)式

8-OH-脫氧鳥嘌呤 性質(zhì)

8-OH-脫氧鳥嘌呤 用途與合成方法

生物活性

8-Hydroxy-2'-deoxyguanosine 是氧化應(yīng)激和致癌反應(yīng)的關(guān)鍵生物標(biāo)志物。

靶點(diǎn)

體外研究

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons.

安全信息

MSDS信息

8-OH-脫氧鳥嘌呤 價(jià)格(試劑級(jí))

8-OH-脫氧鳥嘌呤 上下游產(chǎn)品信息

上游原料

8-Benzyloxy-2'-deoxy-D-guanosine2'-脫氧鳥苷8-溴2‘-脫氧鳥苷