L-半胱亞磺酸

生物活性靶點體外研究 用途與合成方法 MSDS L-半胱亞磺酸價格(試劑級) 上下游產(chǎn)品信息

中文名稱	L-半胱亞磺酸
中文同義詞	L-半胱亞磺酸;3-亞磺基-L-丙氨酸;L-半胱氨酸亞磺酸;Α-氨基-Β-亞磺基丙酸;乙酰半胱氨酸雜質(zhì)25;L-半系八堿酸;乙酰半胱氨酸雜質(zhì)26;(2R)-2-氨基-3-亞磺酰基丙酸
英文名稱	L-CYSTEINESULFINIC ACID
英文同義詞	L-CYSTEINESULFINIC ACID;CYSTEINE(L) SULFINIC ACID;2-amino-3-sulfino-propanoic acid;3-Sulfinoalanine;3-sulphino-L-alanine;L-cysteine sulphinic acid;L-CYSTEINESULFINIC ACID 1-HYDRATE;Carbocysteine Impurity 5
CAS號	1115-65-7
分子式	C3H7NO4S
分子量	153.16
EINECS號	214-228-5
相關(guān)類別	Amino  AcidNeurotransmitters;Excitatory  Amino  Acids;Metabolic  Pathways;Metabolites  and  Cofactors  on  the  Metabolic  Pathways  Chart;Others
Mol文件	1115-65-7.mol
結(jié)構(gòu)式

L-半胱亞磺酸 性質(zhì)

L-半胱亞磺酸 用途與合成方法

生物活性

L-Cysteinesulfinic acid 是一種有效的代謝型谷氨酸受體 (mGluRs) 激動劑，作用于mGluR1，mGluR5，mGluR2，mGluR4，mGluR6 和 mGluR8，pEC50 分別為 3.92，4.6，3.9，2.7，4.0，和 3.94。

靶點

體外研究

L-Cysteinesulfinic acid is an endogenous agonist of a metabotropic receptor coupled to stimulation of phospholipase D (PLD) activity. L-CSA is an endogenous agonist of the PLD-coupled metabotropic excitatory amino acids (EAA) receptor. L-CSA selectively activates the PLD-coupled receptor. 1 mM L-CSA induces a significant increase in PLD activity in hippocampal slices, whereas 1 mM concentrations of L-glutamate, L-aspartate, and L-HCA are without effect. L-CSA elicits a dose-dependent increase in PLD activity in rat hippocampal slices in the presence of iGluR antagonists, with an approximate EC     ₅₀    of 500 uM. The PLD response induced by 1 mM L-CSA is not significantly decreased in the presence of 1 uM tetrodotoxin, suggesting that this response is not dependent upon L-CSA-induced increasesin cell firing.

安全信息

MSDS信息

L-半胱亞磺酸 價格(試劑級)

L-半胱亞磺酸 上下游產(chǎn)品信息