AKT 激酶抑制劑

生物活性靶點體外研究體內(nèi)研究 用途與合成方法 MSDS AKT 激酶抑制劑價格(試劑級) 上下游產(chǎn)品信息

中文名稱	AKT 激酶抑制劑
中文同義詞	AKT 激酶抑制劑;AKT抑制劑(AKT KINASE INHIBITOR);化合物 T10276;3-(2-(4-氨基-1,2,5-惡二唑-3-基)-7-(3-氨基丙氧基)-1-乙基-1H-咪唑并[4,5-C]吡啶-4-基)丙-2-炔-1-醇
英文名稱	AKT Kinase Inhibitor
英文同義詞	AKT Kinase Inhibitor;3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol;2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-;AKT Kinase Inhibitor (2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-);3-[2-(4-amino-1;5-c]pyridin-4-yl]-;5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4;AKT Kinase Inhibitor USP/EP/BP
CAS號	842148-40-7
分子式	C16H19N7O3
分子量	357.37
EINECS號
相關(guān)類別	細(xì)胞生物學(xué)試劑;中藥對照品
Mol文件	842148-40-7.mol
結(jié)構(gòu)式

AKT 激酶抑制劑 性質(zhì)

AKT 激酶抑制劑 用途與合成方法

生物活性

AKT Kinase Inhibitor 是一種具有抗腫瘤活性的 Akt 抑制劑。

靶點

體外研究

The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion.

體內(nèi)研究

Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus.

安全信息

MSDS信息

AKT 激酶抑制劑 價格(試劑級)

AKT 激酶抑制劑 上下游產(chǎn)品信息