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MilliplexCatID.FCYTOMAG-20K-11.FelineCyt

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28-IL-15 Beads-Magnetic Hu Complement Panel 2 QC 1 & 2 40 Pack Magnetic Plates Protein Translation 6-plex Beads Mag 20X 75-TNFα Beads 384-Magnetic 54-IL-23 Beads 384-Magnetic

產(chǎn)品介紹

    基本參數(shù)

    詳細(xì)說(shuō)明

    Replacement Information

    重要規(guī)格表

    Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
    sFas, Flt-3 ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-12 (p40), IL-13, IL-18, KC, MCP-1, PDGF-BB, RANTES, SCF, SDF-1, TNF-αFeMplexLuminex xMAP
    Description
    Catalogue NumberFCYTMAG20KPX19BK
    Trade Name
    • MILLIPLEX

    DescriptionMILLIPLEX MAP Feline Cytokine/Chemokine Magnetic Bead Panel Premixed 19 Plex, FCYTOMAG-20K-PMX Space Saver (Bulk) Packaging
    OverviewENTER PRODUCT OVERVIEW
    Background InformationCytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. A generic term, “cytokines” includes myokines (produced by muscle cells), lymphokines (produced by activated Th cells), interleukins (acting as mediators between T cells) and chemokines (responsible for T-cell migration). One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells and myeloid cells. Consequently, research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process.
    References
    Product Information
    Detection methodLuminex xMAP
    ConfigurationPremixed
    Precision, %
    • Inter-Assay:<20

    • Intra-Assay:<15

    Panel TypeMAGNETIC Cytokines/Chemokines
    Applications
    ApplicationSimultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in feline serum, plasma and cell culture samples.
    Key Applications
    • Multiplexing

    Application Notes? This is an overnight incubation assay (2 hours is not recommended) with a 1-hour incubation with detection antibodies requiring 25 μL of neat plasma or serum, or 25 μL cell culture supernatant per well.
    ? This kit may be used for the analysis of all or any combination of the Feline Cytokine/Chemokine panel analytes in serum, plasma or tissue/cell lysate and culture supernatant.
    Biological Information
    SpecificityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
    Species Reactivity
    • Feline

    Analytes Available
    • sFas

    • Flt-3 ligand

    • GM-CSF

    • IFN-γ

    • IL-1β

    • IL-2

    • IL-4

    • IL-6

    • IL-8

    • IL-12 (p40)

    • IL-13

    • IL-18

    • KC

    • MCP-1

    • PDGF-BB

    • RANTES

    • SCF

    • SDF-1

    • TNF-α

    Cross ReactivityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
    Physicochemical Information
    Sensitivity
    • Refer to kit protocol for sensitivities of individual biomarkers.

    Standard Curve Range
    • sFas, IL-2, GM-CSF, IL-8, IL-12 (p40), IL-13, TNFα: 13.7 – 10,000 pg/mL

    • Flt3 Ligand: 6.9 – 5,000 pg/mL

    • IFNγ, IL-4, IL-6, SCF, SDF-1: 68.6 – 50,000 pg/mL

    • IL-1β: 34.3 – 25,000 pg/mL

    • IL-18, MCP-1: 137.2 – 100,000 pg/mL

    • KC, RANTES: 2.7 – 2,000 pg/mL

    • PDGF-BB: 274.3 – 200,000 pg/mL

    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Usage Statement
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

    Storage and Shipping Information
    Storage ConditionsRecommended storage for kit components is 2 - 8°C.
    Packaging Information
    Material Size96-well plate
    Transport Information
    Supplemental Information
    Specifications
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