詳細說明
別名: 2-Hydroxy-benzoic acid 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide
經驗分子式(希爾表示法) C18H21N3O3
分子量 327.38
產品名稱
Biochem/physiol Actions
RSVA314 is a resveratrol analog that is a potent indirect activator of AMPK (AMP-activated protein kinase). RSVA314 is a potent inhibitor of adipogenesis in vitro in cultured cells and in vivo in mice. Apparently RSVA314 activates AMPK via a mechanism implicating CaMKKβ and LKB1. Also RSVA314 increases intracellular clearance of the amyloidogenic peptide Aβ, the core component of the amyloid plaques.
Features and Benefits
This compound is featured on the AMPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
性質
assay | ≥98% (HPLC) |
form | powder |
color | light orange |
solubility | DMSO: soluble15 mg/mL, clear |
storage temp. | 2-8°C |