• Species Reactivity

  Human

• Specificity

  Detects human Stanniocalcin 1/STC-1 in direct ELISAs and Western blots. In these formats, less than 1% cross?reactivity with recombinant human STC-2 is observed.

• Source

  Polyclonal Goat IgG

• Purification

  Antigen Affinity-purified

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant human Stanniocalcin 1    
  Thr18-Ala247    
  Accession # P52823

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

• Label

  Unconjugated

Applications

• Recommended    
  Concentration

  Sample

• Western Blot

  0.1 μg/mL

  Recombinant Human Stanniocalcin 1

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Reconstitution

  Reconstitute at 0.2 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Stanniocalcin 1/STC-1

Human STC-1 is a secreted disulfide-linked homodimeric phosphorylated glycoprotein hormone (50 kDa and higher molecular weight variants) that is related to the STC protein first discovered from corpuscles of stannius in fish. It is expressed in a wide variety of tissues and has endocrine/paracrine/autocrine functions relating to calcium and phosphate homeostasis, reproduction and development. The 230 amino acid (aa) mature STC-1 contains five intrachain disulfide and one interchain disulfide bond. Human STC-1 and STC-2 share approximately 30% aa sequence homology. STC-1 is highly homologous across species. Human STC-1 shares > 95% sequence homology with mouse, rat, and bovine STC-1.

• Entrez Gene IDs:

  6781 (Human)

• Alternate Names:

  Stanniocalcin 1; stanniocalcin-1; STC1; STC-1; STCSTC-1