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Human CX3CL1/Fractalkine MAb (Clone 81513) 25 UG

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Human CX3CL1/Fractalkine MAb (Clone 81513) 25 UG信息二維碼

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產品介紹

    基本參數(shù)

    詳細說明

    • Species Reactivity

      Human

    • Specificity

      Detects human CX3CL1/Fractalkine Chemokine Domain in direct ELISAs and Western blots.

    • Source

      Monoclonal Mouse IgG    1 Clone # 81513

    • Purification

      Protein A or G purified from hybridoma culture supernatant

    • Immunogen

      NS0 and     E. coli-derived recombinant human CX3CL1/Fractalkine Chemokine Domain    
      Gln25-Arg339 (Ser199Asn)    
      Accession # P78423

    • Formulation

      Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

    • Label

      Unconjugated

    Applications

    • Recommended    
      Concentration

      Sample

    • Western Blot

      1 μg/mL

      Recombinant Human CX3CL1/Fractalkine Full Length (Catalog # )


    • Immunohistochemistry

      8-25 μg/mL

      Immersion fixed paraffin-embedded sections of human Alzheimer's disease brain


    Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

    Preparation and Storage

    • Reconstitution

      Reconstitute at 0.5 mg/mL in sterile PBS.

    • Shipping

      The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

    • Stability & Storage

      Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

      • 12 months from date of receipt, -20 to -70 °C as supplied.

      • 1 month, 2 to 8 °C under sterile conditions after reconstitution.

      • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

    Background: CX3CL1/Fractalkine

    CX3CL1 is a type I membrane protein in which an extracellular chemokine domain possessing a unique C-X3-C cysteine motif is tethered on a long mucin-like stalk. It can also be released as a soluble molecule upon proteolysis at a membrane proximal site.

    • Entrez Gene IDs:

      6376 (Human); 20312 (Mouse); 89808 (Rat)

    • Alternate Names:

      ABCD-3; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C membrane-anchored chemokine; CX3CL1; CXC3; CXC3C; FKN; Fractalkine; Neurotactin; neurotactin); NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine; NTTSmall-inducible cytokine D1; SCYD1C-X3-C motif chemokine 1; small inducible cytokine subfamily D (Cys-X3-Cys), member-1











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