• Species Reactivity

  Mouse

• Specificity

  Detects mouse Cryptic in direct ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant human Cryptic is observed.

• Source

  Monoclonal Rat IgG2b Clone # 221428

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant mouse Cryptic    
  Tyr36-Gly177    
  Accession # P97766

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 700

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 μg/10    ⁶ cells

  D3 mouse embryonic stem cell line

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Cryptic

Cryptic, also known as CFC-1, is a member of the Epidermal Growth Factor-Cripto/FRL-1/Cryptic (EGF-CFC) family of signaling proteins. It is expressed during mesoderm differentation and is necessary for determining left-right asymmetry. Cryptic functions as a co-receptor that regulates signaling by some TGF-beta superfamily members.

• Entrez Gene IDs:

  55997 (Human); 12627 (Mouse)

• Alternate Names:

  CFC1; CFC-1; CFC1B; cripto, FRL-1, cryptic family 1; Cryptic family protein 1; cryptic protein; Cryptic; CRYPTICFLJ77897; HTX2MGC133213