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Human CD96v2 Allophycocyanin MAb (Clone 628211) 100 TESTS

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Human CD96v2 Allophycocyanin MAb (Clone 628211) 100 TESTS信息二維碼

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產(chǎn)品介紹

    基本參數(shù)

    詳細說明

    • Species Reactivity

      Human

    • Specificity

      Detects human CD96 in direct ELISAs.

    • Source

      Monoclonal Mouse IgG    1 Clone # 628211

    • Purification

      Protein A or G purified from hybridoma culture supernatant

    • Immunogen

      Mouse myeloma cell line NS0-derived recombinant human CD96    
      Val22-Asp501    
      Accession # NP_005807

    • Formulation

      Supplied in a saline solution containing BSA and Sodium Azide.

    • Label

      Allophycocyanin

    Applications


    • Recommended    
      Concentration

      Sample

    • Flow Cytometry

      Please refer to the PDF datasheet for specifications.


    Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

    Preparation and Storage

    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

    • Stability & Storage

      Protect from light.    Do not freeze.    

      • 12 months from date of receipt, 2 to 8 °C as supplied.

    Background: CD96

    CD96 (also known as Tactile) is a 160 kDa type I transmembrane glycoprotein that contains three Ig-like domains in its extracellular region. It is expressed on CD4+ and CD8+ T cells, NK cells, and select B cells. CD96 binds to CD155/PVR and participates in NK cell-mediated lysis of CD155+ target cells. Alternate splicing generates a short variant (CD96v2) which lacks 16 amino acids (aa) within the second Ig-like domain. CD96v2 is the predominant isoform in many cell types and exhibits even greater binding affinity with CD155 than does full length CD96. A soluble form of CD96 circulates in the serum. Over aa 22-501, human CD96v2 shares 55% aa sequence identity with mouse and rat CD96.

    • Entrez Gene IDs:

      10225 (Human); 84544 (Mouse); 498079 (Rat)

    • Alternate Names:

      CD96 antigenMGC22596; CD96 molecule; CD96; DKFZp667E2122; T cell-activated increased late expression protein; TACTILE; TACTILEincreased late expression; T-cell surface protein tactile







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