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Human Desmocollin-3 Affinity Purified Polyclonal Ab 25 UG

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Human Desmocollin-3 Affinity Purified Polyclonal Ab 25 UG信息二維碼

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產(chǎn)品介紹

    基本參數(shù)

    詳細(xì)說明

    • Species Reactivity

      Human

    • Specificity

      Detects human Desmocollin-3 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) Desmocollin-2 is observed and less than 1% cross-reactivity with rhDesmocollin-1 is observed.

    • Source

      Polyclonal Sheep IgG

    • Purification

      Antigen Affinity-purified

    • Immunogen

      Mouse myeloma cell line NS0-derived recombinant human Desmocollin-3    
      Arg136-Lys690    
      Accession # Q14574

    • Formulation

      Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

    • Label

      Unconjugated

    Applications

    • Recommended    
      Concentration

      Sample

    • Western Blot

      0.1 μg/mL

      Recombinant Human Desmocollin?3 (Catalog # )


    Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

    Preparation and Storage

    • Reconstitution

      Reconstitute at 0.2 mg/mL in sterile PBS.

    • Shipping

      The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

    • Stability & Storage

      Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

      • 12 months from date of receipt, -20 to -70 °C as supplied.

      • 1 month, 2 to 8 °C under sterile conditions after reconstitution.

      • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

    Background: Desmocollin-3

    The transmembrane cadherin family adhesion molecule Desmocollin-3 is one of the principal components of epithelial cell desmosomes. It can be dysregulated in carcinoma and proteolytically cleaved by caspases and metalloproteases during apoptosis.

    • Entrez Gene IDs:

      1825 (Human); 13507 (Mouse); 307563 (Rat)

    • Alternate Names:

      Cadherin family member 3; CDHF3; CDHF3HT-CP; desmocollin 3; Desmocollin3; Desmocollin-3; desmocollin-4; DSC; DSC1; DSC2; DSC3; DSC4; DSC4desmocollin-3; HT-CP



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