• Species Reactivity

  Human

• Specificity

  Detects human MICA/B in direct ELISAs.

• Source

  Monoclonal Mouse IgG    _2A Clone # 159207

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  BaF3 mouse pro-B cell line transfected with human MICA    
  Accession # Q29983

• Formulation

  Supplied in a saline solution containing BSA and Sodium Azide.

• Label

  Phycoerythrin

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  10 μL/10    ⁶ cells

  See below

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Protect from light.    Do not freeze.    

• 12 months from date of receipt, 2 to 8 °C as supplied.

Background: MICA/B

MICA and MICB are stress-induced type I transmembrane proteins that function as ligands for NKG2D. They are distantly related to MHC class I proteins and are expressed on epithelial tumors and in response to infections.

• Long Name:

  MHC Class I-related Protein A and B

• Entrez Gene IDs:

  4276 (Human)

• Alternate Names:

  MHC class I chain-related protein A; MHC class I chain-related protein B; MIC; MICA; MICA/B; MICB; PERB11; PERB11.1; PERB11.2