• Species Reactivity

  Human

• Specificity

  Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.

• Source

  Monoclonal Mouse IgG    _2A Clone # 350418

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  HEK293 human embryonic kidney cell line transfected with human FPR1    
  Met1-Lys350    
  Accession # NP_002020

• Formulation

  Supplied in a saline solution containing BSA and Sodium Azide.

• Label

  Phycoerythrin

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  10 μL/10    ⁶ cells

  See below

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Protect from light.    Do not freeze.    

• 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FPR1

FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N?formyl?methionyl peptides draws neutrophils to sites of infection and promotes degranulation. In addition, a novel chemokine-like molecule, FAM19A4, has also been shown to bind to FPR1.  Human and mouse FPR1 share 73% amino acid sequence identity.

• Long Name:

  Formyl Peptide Receptor 1

• Entrez Gene IDs:

  2357 (Human); 14293 (Mouse); 292409 (Rat)

• Alternate Names:

  fMet-Leu-Phe receptor; fMLF-R; fMLP receptor; FMLP; formyl peptide receptor 1; FPR1; FPRfMet-Leu-Phe receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor